Group Leader: Dr. Nir Kalisman
Department of Biological Chemistry
The Silberman Institute of Life Sciences
The Hebrew University of Jerusalem
Our lab employs mass spectrometry to resolve diverse open questions in medicine and human biology. One
focus of the lab is to understand the structural basis underlying Facioscapulohumeral muscular dystrophy
(FSHD). Using cutting-edge tools in structural mass spectrometry and cryo-electron microscopy, we solve
the atomic structures of the causative gene in FSHD as it interacts with other transcription activators.
A second focus of the lab is the study of the gut microbiome using meta-proteomics. We develop new tools,
both experimental and computational, to better characterize this enormously complex setting. Come talk to
us if you want to be part this dynamic and exciting era in biology!
News:
Feb. 10 Launching a project to develop new molecular tools for FSHD diagnostics. Suitable for 3rd year B.Sc students.
Jan. 5 We are looking for MSc and PhD students to study the atomic structures of the p53 and DUX4 activation domains.
Jun. 20 Congratulations Tamar for your Analytical Chemistry paper!